Bilateral subclavian vein thrombosis in a patient with acquired immunodeficiency syndrome
D D Bayer1, A F Sorbello, D V Condoluci
1Division of Infectious Diseases, University of Medicine and Dentistry of New Jersey--School of Osteopathic Medicine, Stratford, USA.
Abstract:
Bilateral subclavian vein thrombi developed, in the presence of a Groshong catheter, in a patient with the acquired immunodeficiency syndrome (AIDS) and disseminated cytomegalovirus infection. Thrombosis is an uncommon complication of AIDS, and bilateral subclavian thrombi are rare. Although localized, unilateral thrombi occur in patients with indwelling central venous catheters, unexpectedly extensive bilateral clot formation is seen to develop in patients with human immunodeficiency virus infection. Potentially predisposing factors for thrombosis in AIDS include central venous catheterization, malignancy, elevated anticardiolipin antibodies, alteration of vascular endothelial cell function reflected in low free protein S levels, and enhanced endothelial procoagulant activity related to cytomegalovirus. Anecdotal data strongly suggest that cytomegalovirus enhances the risk for thrombosis, but studies are needed to confirm the association. Physicians should be aware of the enhanced risk for extensive thrombi in AIDS, especially in patients with disseminated cytomegalovirus infection.
More Related Videos
07:21Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
05:51Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein
Published on: January 13, 2026
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Sexually Transmitted Infections
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Venous Thrombosis I: Introduction
Venous Thrombosis III: Interprofessional Care
