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[Cutaneous pulpar temperature and cold test. Predictive specificity and sensitivity in pharmaco-clinical studies]
J S Weil1, A Maurel, R Van Frenkel
1Centre de Recherches du Laboratoire L. Lafon, Maisons-Alfort.
Journal Des Maladies Vasculaires
|January 1, 1995
Summary
This study measured finger temperature changes after cold water immersion in individuals with and without vascular conditions. Patients with Raynaud's phenomenon and acrocyanosis exhibited significantly lower initial finger temperatures, indicating potential circulatory issues.
Area of Science:
- Vascular Physiology
- Thermography
- Medical Diagnostics
Context:
- Assessing peripheral circulation is crucial for diagnosing various vascular conditions.
- Finger temperature is a key indicator of blood flow and vascular health.
- Cold exposure tests are commonly used to evaluate circulatory responses.
Purpose:
- To measure finger cutaneous pulpar temperature.
- To assess temperature changes after cold water immersion and subsequent rewarming.
- To differentiate vascular disease patients from healthy individuals based on thermal response.
Summary:
- 347 subjects (healthy, acrocyanosis, Raynaud's, peripheral arterial occlusive disease, other vascular diseases) underwent a cold immersion test.
- Acrocyanosis and Raynaud's groups showed significantly lower initial finger temperatures (p < 0.02).
- The cooling test identified three distinct temperature reaction patterns, with 100% specificity in detecting abnormal rewarming in subjects with cold hands.
Impact:
- Provides a diagnostic tool for identifying abnormal circulatory responses to cold.
- Highlights the utility of temperature measurement in diagnosing conditions like Raynaud's phenomenon.
- Contributes to understanding the physiological basis of peripheral vascular diseases.