[Informative value of various diagnostic methods in Itsenko-Cushing syndrome]

Area of Science:

• Endocrinology
• Diagnostic Imaging
• Surgical Oncology

Background:

• Icenko-Cushing syndrome presents diagnostic challenges.
• Accurate tumor localization is crucial for effective treatment.
• Evaluating various imaging modalities is essential for optimal patient outcomes.

Purpose of the Study:

• To comparatively evaluate different diagnostic methods for Icenko-Cushing syndrome.
• To assess the efficacy of MR-topography and ultrasonic examination (USE) in diagnosing and localizing adrenal tumors.
• To correlate imaging findings with intraoperative and morphological data.

Main Methods:

• Comparative analysis of diagnostic techniques in 36 patients with Icenko-Cushing syndrome.
• Magnetic Resonance (MR) imaging for topographical assessment.
• Ultrasonic examination (USE) for tumor detection and intraoperative guidance.
• Correlation of imaging results with surgical findings and histopathology.

Main Results:

• MR-topography demonstrated the highest level of informativeness.
• Ultrasonic examination proved highly effective for detecting tumors up to 1 cm.
• Intraoperative USE facilitated tumor localization and assessment of surrounding organ involvement, leading to reduced operative time and less invasive procedures.

Conclusions:

• MR-topography is a key imaging modality for Icenko-Cushing syndrome.
• Ultrasonic examination is valuable for small tumor detection and intraoperative navigation.
• Integrated use of imaging techniques improves surgical outcomes for Icenko-Cushing syndrome.