Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lower limb intra-arterial thrombolysis

J Golledge1, R B Galland

  • 1Department of Vascular Surgery, Royal Berkshire Hospital, Reading, UK.

Postgraduate Medical Journal
|March 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hearing Impairment and Incident Frailty in Later Life: The Health in Men Study (HIMS).

The journal of nutrition, health & aging·2023
Same author

Peripheral arterial disease (PAD) - A challenging manifestation of atherosclerosis.

Preventive medicine·2023
Same author

Comparison of peak wall stress and peak wall rupture index in ruptured and asymptomatic intact abdominal aortic aneurysms.

The British journal of surgery·2021
Same author

Author response to: Peak wall stress and peak wall rupture index in ruptured and asymptomatic intact abdominal aortic aneurysms.

The British journal of surgery·2021
Same author

Systematic approach towards reliable estimation of abdominal aortic aneurysm size by ultrasound imaging and CT.

BJS open·2021
Same author

Effects of quercetin on exercise performance, physical activity and blood supply in a novel model of sustained hind-limb ischaemia.

BJS open·2021

Acute lower limb ischaemia affects 5000 UK patients yearly, primarily caused by thrombosis. Intra-arterial thrombolysis is now a common first-line treatment for this vascular condition.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology

Background:

  • Acute lower limb ischaemia affects approximately 5000 patients annually in the UK.
  • Thromboembolic disease is the usual cause, with thrombosis now being the principal cause (59% of cases) over embolism.
  • Other causes include aortic dissection and arterial trauma.

Purpose of the Study:

  • To highlight the changing aetiology of acute lower limb ischaemia.
  • To emphasize the increasing role of intra-arterial thrombolysis as a primary treatment.

Main Methods:

  • Retrospective analysis of patient data.
  • Review of treatment trends over two decades.

Main Results:

  • Thrombosis has become the leading cause of acute lower limb ischaemia, surpassing embolism.

Related Experiment Videos

  • Intra-arterial thrombolysis is increasingly adopted as the initial treatment strategy.

    • Conclusions:

    • The shift towards thrombosis as the primary aetiology necessitates updated treatment protocols.
    • Intra-arterial thrombolysis represents a significant advancement in managing acute lower limb ischaemia.