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[Gastrointestinal hormones]

D García Compeán1

  • 1Departamento de Medicina Interna Hospital Universitario Dr. José E. González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, México.

Revista De Gastroenterologia De Mexico
|April 1, 1993
PubMed
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Gastrointestinal endocrinology is a growing field, revealing new roles for gut hormones and peptides in both normal and abnormal physiological processes. Biochemical diagnosis is crucial for understanding these complex hormonal functions.

Area of Science:

  • Gastroenterology
  • Endocrinology
  • Neuroscience

Background:

  • Recent advances have expanded knowledge of gastrointestinal (GI) hormone functions.
  • New peptides have been isolated from the GI tract and pancreas.
  • Hormones previously thought to be exclusive to the digestive system are now found in the brain.

Purpose of the Study:

  • To discuss general concepts of GI and pancreatic hormonal physio-pathology.
  • To detail the roles of specific hormones and peptides in biological processes.
  • To highlight the importance of biochemical diagnosis in this field.

Main Methods:

  • Review of current literature on GI hormones and peptides.
  • Discussion of physiological and physiopathological roles.

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  • Emphasis on diagnostic approaches.
  • Main Results:

    • Identification of novel peptides and expanded roles for known hormones.
    • Evidence of GI hormone and peptide presence and activity in the brain.
    • Increased complexity in understanding gut-brain-endocrine interactions.

    Conclusions:

    • The field of "gastrointestinal endocrinology" is emerging due to these complex findings.
    • Understanding the physio-pathology of GI and pancreatic hormones is critical.
    • Biochemical diagnosis is essential for identifying and managing hormonal abnormalities.