Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Retroperitoneal Ewing's sarcoma

M Oya¹, J Nakashima, T Ishii

¹Department of Urology, Keio University School of Medicine, Tokyo, Japan.

Urologia Internationalis

|January 1, 1995

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pharmacokinetics of single-dose sildenafil administered orally in clinically healthy dogs: Effect of feeding and dose proportionality.

Journal of veterinary pharmacology and therapeutics·2018

Same author

Erimopyrone, a Lignan Derivative from the Liverwort Moerckia erimona.

Bioscience, biotechnology, and biochemistry·2016

Same author

Application of cytokine drug delivery systems to the immunotherapy of renal cell carcinoma in mice.

International journal of urology : official journal of the Japanese Urological Association·2013

Same author

Cytokine gene modification of bladder cancer cells for the establishment of bladder cancer vaccine.

International journal of urology : official journal of the Japanese Urological Association·2013

Same author

Newly developed equipment and methods in the treatment of BPH: analysis of present status.

International journal of urology : official journal of the Japanese Urological Association·2013

Same author

Non-targeted analyses of animal plasma: betaine and choline represent the nutritional and metabolic status.

Journal of animal physiology and animal nutrition·2011

A rare retroperitoneal extraskeletal Ewing's sarcoma was surgically removed with the kidney and ureter. Adjuvant chemotherapy (T-11 regimen) effectively prevented tumor recurrence, offering a successful treatment strategy.

Area of Science:

Oncology
Surgical Pathology
Immunohistochemistry

Background:

Extraskeletal Ewing's sarcoma (EES) is a rare malignant bone tumor that can occur in soft tissues.
Retroperitoneal tumors present diagnostic and surgical challenges due to their location and potential for extensive infiltration.

Observation:

A case of EES was identified in the retroperitoneal cavity.
The tumor infiltrated the left kidney and a portion of the left ureter, necessitating en bloc resection.
Histopathological confirmation was achieved through electron microscopy and immunohistochemical staining.

Findings:

A novel monoclonal antibody (5C11) demonstrated specific reactivity with the Ewing's sarcoma cells, aiding in definitive diagnosis.
Surgical excision of the tumor along with involved organs was performed.

Related Experiment Videos

Adjuvant chemotherapy utilizing the T-11 regimen was administered post-operatively.

Implications:

This case highlights the successful surgical management of a rare retroperitoneal EES.
The T-11 chemotherapy regimen proved effective in preventing tumor recurrence, suggesting its potential as a successful adjuvant therapy.
The utility of the 5C11 antibody in diagnosing Ewing's sarcoma is demonstrated.