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[Mumps epidemiology--worldwide]
1Schweizerisches Serum- und Impfinstitut, Bern.
Abstract:
Mumps is an acute viral infection that is endemic worldwide and that occurs primarily in school-age children and adolescents. The most prominent manifestation is tender swelling of the parotid gland. The course of the disease is usually mild and selflimited. Meningitis and orchitis, the latter more common in postpubertal persons, are less frequent manifestations of this disease. As characteristic of many viral infections the severity of the illness increases with age. In the present review first the most important epidemiologic parameters of mumps are presented, as well as the various clinical manifestations and complications. Further the epidemiology of mumps in developing and in industrialized countries is discussed. Breakthrough infections with mumps occurring with either low or high vaccination coverage are described.
Insights
Mumps is a worldwide viral infection mainly affecting children, causing parotid gland swelling. This review covers mumps epidemiology, clinical features, complications, and vaccine breakthrough infections.
Area of Science:
- Virology
- Epidemiology
- Public Health
Context:
- Mumps is a global viral illness primarily impacting school-aged children and adolescents.
- Characterized by parotid gland swelling, mumps is typically mild but can lead to complications like meningitis and orchitis.
- Disease severity often correlates with increasing age.
Purpose:
- To present key epidemiologic parameters of mumps.
- To detail the clinical manifestations and potential complications of mumps.
- To discuss the epidemiology of mumps in diverse global settings and analyze breakthrough infections.
Summary:
- This review synthesizes current knowledge on mumps, including its worldwide endemic nature and primary demographic affected.
- It elaborates on the characteristic parotid gland swelling, disease course, and less common but significant complications such as meningitis and orchitis.
- The review also examines mumps epidemiology across developing and industrialized nations and investigates breakthrough infections in vaccinated populations.
Impact:
- Provides a comprehensive overview of mumps epidemiology and clinical presentation.
- Informs public health strategies for mumps control and prevention.
- Highlights the challenges of mumps in the context of vaccination, including breakthrough infections.