[Fibrinogen level in patients with type I diabetes with and without retinopathy]

Literature data are fairly inconsistent with regard to the plasma fibrinogen levels in type I diabetic patients, and the selection of patients was poorly standardised. We monitored plasma fibrinogen levels in type I diabetics with and without retinopathy. Regardless of the occurrence of diabetic retinopathy, diabetics with good metabolic control did not show significant difference in plasma fibrinogen levels compared to healthy controls. In the randomized group of diabetics plasma fibrinogen was significantly increased compared to diabetics with good metabolic control. This finding points to the potential role of metabolic control and/or vascular complications of diabetes in the maintaining of plasma fibrinogen levels unchanged.