Median nerve somatosensory evoked potentials in children receiving ECMO

Somatosensory evoked potentials (SEPs) were recorded from 11 patients receiving venoarterial extracorporeal membrane oxygenation (ECMO). Cortical responses recorded from the right and left hemispheres were compared to those from 2 other groups of children who were not receiving ECMO. One group consisted of 99 brain-injured patients, while the other consisted of a group of 17 neurologically normal controls. SEP responses from each hemisphere were categorized into 3 grades based on the N20 component--normal latency, abnormal (latency increased > 3 S.D.), or absent. For ECMO patients, 15% of tests disclosed a disagreement between the right and left hemispheres, while 27% of tests from the control group revealed a disagreement between the right and left hemispheres. SEPs were normal over the right hemisphere in 9 patients. Central conduction times obtained from the right and left hemispheres were similar in ECMO patients and were not different from those recorded from a group of patients suffering hypoxic-ischemic injuries and a group of normal controls who did not receive ECMO. The results of this pilot study suggest that SEPs may be employed to evaluate ECMO patients as they are in other brain-injured patients.