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Stevens-Johnson syndrome and abnormal root development: a case report

U Brook1

  • 1Department of Pediatrics, Wolfson Medical Center, Holon, Israel.

International Journal of Paediatric Dentistry
|June 1, 1994
PubMed
Summary
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A 9-year-old boy experienced Stevens-Johnson syndrome after theophylline treatment for asthma. Dental radiography at age 14 revealed arrested root development in his permanent teeth.

Area of Science:

  • Pediatric Pulmonology
  • Dermatology
  • Dental Medicine

Background:

  • A pediatric patient with a history of bronchial asthma since infancy was prescribed slow-release theophylline.
  • The patient developed Stevens-Johnson syndrome, a severe mucocutaneous reaction, approximately two weeks after initiating theophylline therapy.

Observation:

  • The patient presented for dental evaluation at 14 years of age.
  • Panoramic radiography revealed significant arrested root development in the permanent dentition.

Findings:

  • A potential association between Stevens-Johnson syndrome, theophylline use, and subsequent dental developmental anomalies is suggested.
  • The case highlights a possible link between severe drug reactions and long-term effects on tooth development.

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Implications:

  • This case underscores the importance of monitoring for adverse drug reactions in pediatric patients.
  • Further research may be warranted to explore the potential impact of Stevens-Johnson syndrome and its treatments on dental development.
  • Clinicians should consider the possibility of dental abnormalities in patients with a history of severe cutaneous adverse drug reactions.