Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic neuritis: guidelines

S H Wray1

  • 1Department of Neurology, Massachusetts General Hospital, Boston, USA.

Current Opinion in Neurology
|February 1, 1995
PubMed
Summary
This summary is machine-generated.

High-dose corticosteroids for optic neuritis significantly reduce the development of multiple sclerosis over two years. This Optic Neuritis Treatment Trial finding impacts demyelinating disease therapy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paraneoplastic upbeat nystagmus.

Neurology·2011
Same author

The judgement of absence in neglect.

Neuropsychologia·1998
Same author

Pupil dilation to tropicamide is not specific for Alzheimer disease.

Archives of neurology·1997
Same author

Functional MR of brain activity and perfusion in patients with chronic cortical stroke.

AJNR. American journal of neuroradiology·1995
Same author

MR of the brain in mitochondrial myopathy.

AJNR. American journal of neuroradiology·1995
Same author

Visual processing in migraineurs.

Brain : a journal of neurology·1995
Same journal

Movement disorders and Parkinson's disease: collaborative and interdisciplinary research to advance understanding of neural circuit dysfunction, pathophysiology, and care: new horizons in technology, neuroimaging, neurophysiology, and genetics toward personalized medicine.

Current opinion in neurology·2026
Same journal

Editorial introduction.

Current opinion in neurology·2026
Same journal

Multimodal mapping of balance dysfunction in Parkinson's disease: a consensus roadmap for research and intervention.

Current opinion in neurology·2026
Same journal

Tourette syndrome: brain neurophysiology, circuit dysfunction, and neuromodulation across invasive and noninvasive approaches.

Current opinion in neurology·2026
Same journal

Dystonia: from phenotypes to genetics and therapeutic advances.

Current opinion in neurology·2026
Same journal

What can we learn from eye movements in movement disorders and Parkinson's disease?

Current opinion in neurology·2026
See all related articles

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Neurology

Background:

  • Demyelinating diseases, such as multiple sclerosis, pose significant challenges in neurological and ophthalmic care.
  • Optic neuritis is often an early manifestation of multiple sclerosis, making its treatment crucial for disease progression management.

Purpose of the Study:

  • To review the impact of the Optic Neuritis Treatment Trial findings on the management of demyelinating diseases.
  • To highlight the therapeutic implications of high-dose corticosteroid treatment for acute optic neuritis.

Main Methods:

  • The review focuses on evidence accumulated over six years by the Optic Neuritis Treatment Trial.
  • Analysis of treatment outcomes for patients with isolated acute optic neuritis receiving high-dose corticosteroids.

Related Experiment Videos

Main Results:

  • High-dose corticosteroid therapy for acute optic neuritis was shown to reduce the rate of multiple sclerosis development.
  • This effect was observed over a 2-year follow-up period post-treatment.

Conclusions:

  • The Optic Neuritis Treatment Trial provides a major breakthrough in the therapy of demyelinating diseases.
  • Findings have immediate implications for neuro-ophthalmic and neurologic practice in managing patients at risk for multiple sclerosis.