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Percutaneous transluminal angioplasty of infrainguinal vein graft stenosis: long-term outcome

P Dunlop1, K Varty, T Hartshorne

  • 1Department of Surgery, Leicester Royal Infirmary, UK.

The British Journal of Surgery
|February 1, 1995
PubMed

Insights

Percutaneous transluminal angioplasty (PTA) effectively treats infrainguinal vein graft stenosis initially. However, a high restenosis rate, particularly in distal grafts, necessitates further investigation into optimal management strategies.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology

Background:

  • Infrainguinal vein graft stenosis is a significant complication impacting graft patency.
  • Early detection through graft surveillance is crucial for timely intervention.

Purpose of the Study:

  • To evaluate the long-term outcomes of infrainguinal vein graft stenosis treated with percutaneous transluminal angioplasty (PTA) as the primary therapy.
  • To identify factors associated with restenosis after PTA.

Main Methods:

  • Prospective study of 33 infrainguinal vein graft stenoses treated with PTA.
  • Follow-up duration ranged from 18 to 56 months (median 39 months).
  • Analysis of restenosis rates based on graft location and type.

Main Results:

  • Successful treatment with a single PTA in 19 out of 33 cases.
  • Recurrence of stenosis observed in 14 cases at a median of 8.5 months post-PTA.
  • Higher restenosis rates were noted in the distal third of grafts (P=0.002) and in situ vein grafts (P=0.03).

Conclusions:

  • Single-session PTA can achieve initial success in managing infrainguinal vein graft stenosis.
  • Distal graft location and in situ vein grafts are associated with increased risk of restenosis.
  • Optimal management strategies for recurrent infrainguinal vein graft stenosis require further research.

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