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Estrogen dependent LDH-Y, a new LDH isozyme and fertility factor in mice uterus during early pregnancy
P P Singh1, V N Singh, S K Sirmour
1University Department of Zoology, Bhagalpur University, India.
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|April 1, 1995
Abstract:
In estrogen treated ovariectomized and pregnant mice on the first day after mating a sixth LDH isozyme appeared at Relative mobility (Rm) 0.08 to 0.15 and for convenience this isozyme is provisionally designated as LDH-Y. The appearance of a sixth LDH isozyme (LDH-Y) in mice uterus after ovariectomy and estrogen treatment favours the idea that this isozyme is estrogen dependent. Presence of this LDH-Y in mice uterus during preimplantation and finally its sudden disappearance during implantation and post implantation periods further suggest that LDH-Y is estrogen dependent and responsible for restoring fertility in mice.