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[Yearly changes of isolated organisms from the respiratory tract in Hokusho Central Hospital]
1Laboratory of Microbiology and Internal Medicine, Hokusho Central Hospital.
Abstract:
Isolated organisms from the respiratory tract have been studied in our hospital from 1986 to 1993. The total number of samples were 18,345 and samples which showed 10(5) cfu/ml organisms were 8648 in our hospital for 8 years. Enterobacteriacae, Pseudomonas aeruginosa, Haemophilus influenzae, Streptococcus pneumoniae, and glucose nonfermenting gram-negative rods were major isolates in 8 years. Haemophilus influenzae, which used to be the commonest isolate, decreased from 10.9% in 1993 while Enterobacteriacae increased from 8.9% in 1986 to 17.6% in 1993. S. pneumoniae and H. influenzae were major isolates from out-patients consisting of 50%, followed by Enterobacteriacae, P. aeruginosa and MSSA. Enterobacteriacae and P. aeruginosa were major isolates from in-patients, followed by MRSA and beta-Streptococcus. Streptococcus agalactiae, Serratia marcescens and Corynebacterium spp. prevailed especially in the geriatric ward. S. pneumoniae, H. influenzae and M. catarrhalis were major isolates from patients with pneumoconiosis, especially in winter.
Insights
Respiratory tract infections show shifting bacterial trends. Enterobacteriaceae increased, while Haemophilus influenzae decreased in prevalence over eight years, impacting common isolates.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Context:
- This study analyzes respiratory tract microbial isolates from a single hospital between 1986 and 1993.
- A total of 18,345 samples were processed, with 8,648 yielding significant bacterial growth (≥10^5 cfu/ml).
Purpose:
- To track changes in the prevalence of major respiratory pathogens over an eight-year period.
- To identify common bacterial isolates in different patient groups (outpatients, inpatients, geriatric, pneumoconiosis).
Summary:
- Enterobacteriaceae and Pseudomonas aeruginosa emerged as leading isolates in inpatients, while Streptococcus pneumoniae and Haemophilus influenzae were common in outpatients.
- A notable shift was observed: Haemophilus influenzae prevalence decreased, while Enterobacteriaceae significantly increased from 8.9% to 17.6% during the study period.
- Specific organisms like Streptococcus agalactiae, Serratia marcescens, and Corynebacterium spp. were prevalent in geriatric wards, and S. pneumoniae, H. influenzae, and M. catarrhalis in pneumoconiosis patients, particularly during winter.
Impact:
- Highlights evolving antimicrobial resistance patterns and potential shifts in causative agents of respiratory infections.
- Provides valuable epidemiological data for guiding empirical treatment strategies and infection control measures.
- Informs public health surveillance and clinical decision-making regarding respiratory pathogens.