[Non-protein sulfhydryl groups in the blood of patients with stenocardia induced by physical stress]

Patients suffering from stress-induced angina pectoris subjected to exertion show a decreased level of non-protein SH-groups in blood plasma and erythrocytes which depends on the level of myocardial hypoxia and may indicate metabolic exhaustion of the organism. Lowered concentrations of non-protein SH-groups are not a result of lipid peroxidation. Adrenalin is known to antagonize the depletion of non-protein SH-groups under exertion, while noradrenaline promotes the process of their oxidation. When the level of non-protein SH-groups decreases under exertion, the content of atherogenic lipids in blood does not increase, which implies that SH-groups are involved into the mechanism of appearance of atherogenic lipids in blood under exertion.