Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Protein contact dermatitis: myth or reality?

V Janssens1, M Morren, A Dooms-Goossens

  • 1Department of Medical Research (Dermatology), University Hospital, Katholieke Universiteit Leuven, Belgium.

The British Journal of Dermatology
|January 1, 1995
PubMed
Summary

Protein contact dermatitis, a skin condition, causes eczema flare-ups after allergen exposure. Diagnosis often requires scratch or prick tests, as standard patch tests are typically negative.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dietary supplementation of cystinotic mice by lysine inhibits the megalin pathway and decreases kidney cystine content.

Scientific reports·2023
Same author

Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo.

Oncogene·2017
Same author

Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model.

Endocrinology·2016
Same author

A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.

Endocrinology·2015
Same author

The role and therapeutic potential of Ser/Thr phosphatase PP2A in apoptotic signalling networks in human cancer cells.

Current molecular medicine·2012
Same author

The Accelerating Access Initiative: experience with a multinational workplace programme in Africa.

Bulletin of the World Health Organization·2009

Area of Science:

  • Dermatology
  • Allergology
  • Immunology

Background:

  • Protein contact dermatitis is a skin condition characterized by chronic eczema and acute exacerbations.
  • Symptoms appear shortly after exposure to the causative allergen.
  • Standard patch tests for diagnosis are frequently negative.

Purpose of the Study:

  • To clarify the diagnostic challenges and clinical presentation of protein contact dermatitis.
  • To review existing literature on this dermatosis.

Main Methods:

  • Literature review of reported cases of protein contact dermatitis.
  • Analysis of diagnostic methods including patch tests, scratch tests, prick tests, and specific IgE antibody detection.

Main Results:

Related Experiment Videos

  • Patch tests are often negative in protein contact dermatitis.
  • Scratch or prick tests are more reliable for diagnosis.
  • Detection of specific IgE antibodies in blood may be observed.

Conclusions:

  • Protein contact dermatitis is a distinct dermatosis requiring specific diagnostic approaches.
  • Accurate diagnosis relies on methods beyond standard patch testing.
  • Further research is needed to fully understand this condition.