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Diffuse idiopathic skeletal hyperostosis in a Nigerian (DISH Forestier's disease, ankylosing hyperostosis): a case

O O Adelowo1

  • 1Department of Medicine, Ogun State University Teaching Hospital, Sagamu.

West African Journal of Medicine
|October 1, 1994
PubMed

Abstract:

A 61 year old diabetic patient with Diffuse Idiopathic Skeletal Hyperostosis is presented. There has been only one report of this rare disease in an African.

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

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