Immunological consequences of burn injury in children

The authors investigated immunological changes after burn injury in children. Relevant findings were observed in the following immunological factors: phagocytose activity, T-lymphocytes, active T-lymphocytes, test of blastic transformation of lymphocytes and immunoglobulins. The findings confirm from an immunological point of view the requirement of early necrectomy (at the latest on day 4 or 5 after injury). Later necrectomy cannot prevent immunosuppression after burn injury but itself causes deterioration of the immunological status of patient. Adequate therapy can improve the immunological status of burned patients.