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Related Experiment Videos

Leukomyelopathy in ataxic calves

Y Seimiya1, K Okada, K Ohshima

  • 1Morioka Livestock Hygiene Service Center, Iwate, Japan.

The Journal of Veterinary Medical Science
|February 1, 1995
PubMed
Summary

Ataxic disease in calves caused spinal cord lesions, but the cause remains unknown despite vitamin therapy showing partial recovery. Further research is needed to identify the etiology of this calf ataxia.

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Area of Science:

  • Veterinary Neurology
  • Pathology
  • Animal Science

Background:

  • Ataxia, a neurological disorder, affected a group of fattening calves.
  • The condition manifested over a four-month period in calves aged 6 to 15 months.

Purpose of the Study:

  • To investigate the clinical and pathological characteristics of an ataxic disease in fattening calves.
  • To explore potential etiological factors contributing to the observed ataxia.

Main Methods:

  • Clinical observation of 73 affected calves.
  • Examination of 14 ataxic animals, including histopathological and ultrastructural analysis of spinal cord tissue.
  • Pathogen isolation attempts from visceral organs.
  • Serum copper level determination.

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Main Results:

  • Bilateral vacuolation and axonal degeneration in the spinal white matter were the principal lesions.
  • Ultrastructural examination revealed vacuoles in periaxonal areas with dissociated myelin lamellae.
  • Partial recovery (10 calves) was observed following vitamin administration and needle puncture therapy.
  • No pathogens were isolated, and serum copper levels were within the normal range.

Conclusions:

  • The study identified specific spinal cord lesions associated with calf ataxia.
  • Despite extensive examination, the etiological factors of this ataxic disease remain undetermined.
  • Further investigation is warranted to elucidate the cause of this neurological condition in calves.