Related Experiment Videos
Activation of ryanodine receptors by flash photolysis of caged Ca2+
1School of Zoology, La Trobe University, Bundoora, Melbourne, Victoria, Australia.
Biophysical Journal
|March 1, 1995
Abstract:
Flash photolysis of DM-nitrophen generates an extremely large [Ca2+] transient ("Ca2+ spike") at the start of each Ca2+ "step." The Ca2+ spike greatly increases the speed of activation of the ryanodine receptor channel ("supercharging") and could be responsible for apparent channel adaptation.