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CNPase expression in the developing opossum brain stem and cerebellum
P C Barradas1, S S Gomes, L A Cavalcante
1Instituto de Biofisica C. Chagas Filho, UFRJ, Brazil.
Abstract:
Immunoreactivity to 2',3' cyclic nucleotide 3' phosphohydrolase (CNPase; EC 3.1.4.37) was studied in the developing opossum brain stem and cerebellum. Regional differences were found in oligodendrocytes concerning the time of appearance (early: medical longitudinal fascicle [mlf]; intermediate: inferior colliculus [IC], deep layers of the superior colliculus [SC] and white matter of cerebellar folia; late: optic layer of SC) and duration of immunoreactivity (short: optic layer of SC; intermediate: mlf; long: cerebellar folia, etc). The results suggest that regional heterogeneities in CNPase expression are linked to intrinsic properties of local and afferent axons.