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Profiles for the analysis of immunoglobulin sequences: comparison of V gene subgroups
1Bristol-Myers Squibb Pharmaceutical Research Institute, Seattle, Washington 98121, USA.
Protein Science : a Publication of the Protein Society
|February 1, 1995
Abstract:
A format for the structure-oriented analysis of immunoglobulin (Ig) variable region sequences is presented and applied to generate sequence profiles for comparison of heavy- and light-chain subgroups. The profile allows simultaneous evaluation of sequences and structural information and can be used for a number of different applications.