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Updated: Jul 26, 2026

In vitro Measurements of Tracheal Constriction Using Mice
Published on: June 25, 2012
[Adrenergic and cholinergic regulation of respiratory efficiency of secretory cells]
Abstract:
The influence of sympathetic and parasympathetic systems on the secretory cell respiration is mediated at the subcellular level by adreno- and cholinoreceptors of plasmatic membranes and is related to selective oxidation of two different substrates of the Krebs cycle: succinate and alpha-ketoglutarate, both being involved into two reciprocal mediator-hormonal-substrate-nucleotide systems: catecholamines-succinate-cAMP-ATP and acetylcholint-alpha-ketoglutarate-cGMP-GTP. The reciprocation of these systems is necessary for regulation of cell oxygen demand and effective oxygen utilization for ATP-synthesis and synthesis of other macroergical compounds depending on the functional state of a cell.
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