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Unusual pattern of gastric and hepatic infiltration in an infant with acute monocytic leukemia
U Kontny1, P Gutjahr, R Schumacher
1Children's Hospital, Johannes Gutenberg University Mainz, Germany.
Pediatric Radiology
|January 1, 1995
Insights
A rare case of acute monocytic leukemia in a 10-month-old girl revealed unusual stomach and liver infiltrates on ultrasound. The findings highlight atypical presentations of pediatric leukemia.
Area of Science:
- Pediatric Oncology
- Medical Imaging
- Hematology
Background:
- Acute monocytic leukemia (AML) is a rare subtype of acute myeloid leukemia.
- Leukemia infiltration in pediatric patients can manifest in various organs.
- Abdominal ultrasound is a common diagnostic tool in evaluating pediatric abdominal masses and organomegaly.
Observation:
- Ultrasound imaging of a 10-month-old girl with acute monocytic leukemia demonstrated atypical leukemic infiltrates.
- Gastric involvement presented as intraluminal polyps within the stomach wall.
- Hepatic infiltration was uniquely localized to the portal vessels.
Findings:
- The study identifies unusual patterns of leukemic infiltration in the stomach and liver in a pediatric patient with acute monocytic leukemia.
- Intraluminal polyps in the stomach represent a rare manifestation of leukemic infiltration.
- Portal vessel-confined hepatic infiltration is an uncommon finding in pediatric leukemia.
Implications:
- These findings expand the understanding of the diverse imaging appearances of pediatric acute monocytic leukemia.
- Recognizing these unusual patterns is crucial for accurate diagnosis and timely treatment initiation in affected children.
- Further research into the specific mechanisms driving these atypical infiltrates may improve therapeutic strategies.
Abstract:
A 10-month-old girl with acute monocytic leukemia is presented. Ultrasound of the abdomen on admission showed an unusual distribution of leukemia infiltrates in the stomach and liver. The leukemic infiltrates in the wall of the stomach presented as intraluminal polyps, while the leukemic infiltration of the liver was strictly confined to the portal vessels.