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Calcifying arteriopathy in the basal ganglia in human immunodeficiency virus infection

H Bode1, C Rudin

  • 1Universitätskinderklinik, Ulm, Germany.

Pediatric Radiology
|January 1, 1995
PubMed

Insights

Early ultrasound in infants with human immunodeficiency virus (HIV) can detect HIV encephalopathy before symptoms appear. This imaging technique identified lenticulostriate arteriopathy, a key indicator of the condition.

Area of Science:

  • Pediatric Neurology
  • Neuroimaging
  • Infectious Diseases

Background:

  • Human immunodeficiency virus (HIV) infection can lead to neurological complications in children, known as HIV encephalopathy.
  • Early detection of HIV encephalopathy is crucial for timely intervention and management.

Observation:

  • Echogenic stripes in the basal ganglia were identified sonographically in a 4-month-old infant with HIV infection.
  • This finding represented lenticulostriate arteriopathy, correlating with early histological changes of HIV encephalopathy.

Findings:

  • Cerebral sonography identified lenticulostriate arteriopathy in an infant with HIV.
  • CT scan at 3 years and 5 months showed calcification but no progressive encephalopathy.
  • The child maintained normal mental and motor development.

Implications:

  • Cerebral sonography in early infancy can identify HIV encephalopathy before clinical manifestations.
  • This imaging approach may facilitate earlier diagnosis and management of neurological complications in HIV-infected infants.

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