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[Otosclerosis. Immunoendocrine and infective aspects]
A Di Nardo1, C Parlapiano, M Di Prima
1II Clinica Medica, Università degli Studi La Sapienza, Roma.
Rivista Europea Per Le Scienze Mediche E Farmacologiche = European Review for Medical and Pharmacological Sciences = Revue Europeenne Pour Les Sciences Medicales Et Pharmacologiques
|September 1, 1993
Abstract:
The etiopathogenesis of otosclerosis is yet scarcely known. In this paper we focus on the immunoendocrine and infective aspects of the disorder. According to recent investigations the role played by cytokines and calcitonin's receptors appears to be crucial in the pathogenesis of otosclerosis. In addition, the ultrastructural and immunohistochemical evidence of virus specific antigens around the active otosclerotic focus suggest that virus can trigger and maintain an inflammatory disease.