The effect of Taleum (sodium cromoglycate) 1-mg inhalation aerosol in children with allergic asthma

Related Experiment Video

Updated: Aug 2, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

B Nagy1

  • 1Department of Pediatrics, University Medical School, Debrecen, Hungary.

Therapia Hungarica (English Edition)
|January 1, 1994
PubMed

Insights

Taleum (sodium cromoglycate) inhalation aerosol demonstrated comparable effectiveness to Intal powder for managing extrinsic bronchial asthma in children. This study highlights Taleum

Area of Science:

  • Pediatric Pulmonology
  • Pharmacology
  • Allergy and Immunology

Background:

  • Extrinsic bronchial asthma is a common chronic respiratory condition in children.
  • Effective prophylactic treatments are crucial for managing asthma symptoms and improving respiratory function.
  • Sodium cromoglycate is an established mast cell stabilizer used in asthma management.

Purpose of the Study:

  • To evaluate the clinical usefulness and prophylactic efficacy of Taleum (sodium cromoglycate) inhalation aerosol.
  • To compare the effects of Taleum spray with Intal powder (sodium cromoglycate) delivered via spinhaler.
  • To assess changes in clinical symptoms and respiratory function in children with extrinsic bronchial asthma.

Main Methods:

  • A study involving 34 children aged 8 to 14 years with extrinsic bronchial asthma.
  • Administration of Taleum inhalation aerosol and Intal powder via spinhaler.
  • Comparison of clinical symptom changes and respiratory function parameters between the two treatment groups.

Main Results:

  • Children easily learned to use the Taleum spray inhalation method.
  • Taleum spray offered a simpler administration compared to Intal powder capsules.
  • The overall effectiveness of Taleum was found to be similar to that of Intal capsule.

Conclusions:

  • Taleum (sodium cromoglycate) inhalation aerosol is a useful and effective prophylactic agent for childhood extrinsic bronchial asthma.
  • The spray formulation of Taleum provides a simpler and easily learned method of administration.
  • Taleum offers comparable therapeutic benefits to Intal in managing pediatric asthma.

More Related Videos

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing09:29

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

Published on: May 13, 2020

Related Concept Videos

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Inhaled Medications01:23

Inhaled Medications

Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...