Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Concepts underlying autotransplants for cancer

R P Gale1, A Butturini

  • 1Department of Medicine, UCLA School of Medicine, USA.

Wiener Medizinische Wochenschrift (1946)
|January 1, 1995
PubMed
Summary

This review examines autotransplants for cancer treatment, questioning if intensive chemotherapy is superior and if immune effects influence outcomes post-transplant. It also assesses the necessity and risks associated with autotransplants and graft relapse.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Potential Habitability of Present-Day Martian Subsurface for Earth-Like Methanogens.

Astrobiology·2025
Same author

Origin, accumulation and fate of dissolved organic matter in an extreme hypersaline shallow lake.

Water research·2022
Same author

Dissolved organic matter in a tropical saline-alkaline lake of the East African Rift Valley.

Water research·2020
Same author

Can Long-Term Bone Marrow Culture Eliminate Leukemia Cells?

Leukemia & lymphoma·2016
Same author

Hydrological conditions control in situ DOM retention and release along a Mediterranean river.

Water research·2016
Same author

The effects of sediment depth and oxygen concentration on the use of organic matter: An experimental study using an infiltration sediment tank.

The Science of the total environment·2015

Area of Science:

  • Oncology
  • Transplantation Medicine
  • Cancer Immunology

Background:

  • Autotransplants are utilized in cancer therapy.
  • The optimal role and specific benefits of autotransplants remain areas of active investigation.
  • Understanding the underlying concepts is crucial for refining treatment strategies.

Purpose of the Study:

  • To review key concepts related to autotransplants in cancer treatment.
  • To evaluate the efficacy and risks of intensive chemotherapy in conjunction with autotransplants.
  • To explore the potential for immune-mediated anti-cancer effects post-transplantation.

Main Methods:

  • Literature review of existing studies and concepts.
  • Analysis of treatment intensification strategies.
  • Discussion of graft relapse risks versus therapeutic benefits.

Main Results:

  • The review synthesizes current understanding of autotransplant principles.
  • It highlights ongoing debates regarding the necessity and optimal application of autotransplants.
  • Consideration is given to the comparative benefits of blood versus bone marrow autotransplants.

Conclusions:

  • Further research is needed to clarify the precise role of autotransplants in cancer care.
  • The balance between chemotherapy intensity, transplant necessity, and relapse risk requires careful consideration.
  • Investigating immune-mediated effects may reveal new therapeutic avenues.

Related Experiment Videos