[Quantitative analysis of the ultrastructure of tumor tissue cell cultures]

Morphometry was applied to the study of the fine structure of the mitochondria, ergastoplasma and polyribosomal apparatus of the cells of the primary and continuous cultures of the tumour tissues. Both among the primary and among the continuous cultures there can be found marked differences in the fine structure of the cells of individual strains. However, as a whole these groups displayed a significant difference by organization of the cytoplasmic protein-synthesizing apparatus. Of the continuous cultures characteristic is a more reduced ergastoplasm and more marked polyribosomal apparatus. It can be supposed that for the tumour cells cultivation on glass served as a factor promoting a further reconstruction of the protein-synthesizing apparatus on the synthesis of the substrates necessary for the growth and multiplication of the cell mass.