Related Experiment Videos
Flunitrazepam for sleep disturbance in children with intractable epilepsy
T Konishi1, K Masuko, Y Naganuma
1Department of Pediatrics, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Brain & Development
|January 1, 1995
Abstract:
Add-on therapy with flunitrazepam (FNZ) was performed in 5 children with marked sleep disturbance and intractable seizures. Correction of the sleep disturbance was attained immediately after the start of FNZ administration in all patients. Furthermore, a significant decrease in the seizure frequency (3 patients) and improved quality of life (4 patients) were concomitantly observed. There was no adverse effect or interaction with conventional AEDs on long-term use.