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Arthritis after mumps and measles vaccination

M Nussinovitch1, L Harel, I Varsano

  • 1Department of Pediatrics C, Children's Medical Center of Israel, Petach, Tikvah.

Archives of Disease in Childhood
|April 1, 1995
PubMed

Insights

Measles, mumps, and rubella (MMR) vaccination can cause joint issues in young children. A case report details acute monoarthritis in a boy

Area of Science:

  • Pediatric rheumatology
  • Vaccine immunology

Background:

  • Measles, mumps, and rubella (MMR) vaccine is widely administered to children.
  • Joint symptoms, including arthritis, have been anecdotally associated with MMR vaccination.

Observation:

  • A pediatric case of acute monoarthritis affecting the knee is presented.
  • The patient developed symptoms following measles and mumps vaccination.

Findings:

  • Synovial fluid analysis revealed a high white blood cell count (4.3 x 10^9/L).
  • The mumps component of the vaccine is suspected as the primary cause of the acute monoarthritis.

Implications:

  • This case highlights a potential adverse reaction to the mumps vaccine component.
  • Further investigation into vaccine-induced arthropathies is warranted to understand the underlying mechanisms.

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