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Updated: Jul 27, 2026

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DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)
Published on: July 15, 2011
The effect of colony age on PCR fingerprinting
H L Coutinho1, B A Handley, H E Kay
1School of Biological Sciences, University of Bristol, UK.
Letters in Applied Microbiology
|December 1, 1993
Abstract:
The pattern of DNA fragments produced by the polymerase chain reaction using arbitrary primers is strongly influenced by the age of the colonies sampled. We show that the number, clarity and reproducibility of the bands produced is optimal when very young colonies are sampled.

