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Diterpene glycosides from Iphiona aucheri

E Roeder1, T Bourauel, U Meier

  • 1Pharmazeutisches Institut, Universität Bonn, F.R.G.

Phytochemistry
|September 1, 1994
PubMed
Summary

Iphiona aucheri poisoning in racing camels was investigated. Atractyloside and carboxyatractyloside were identified as the toxic compounds responsible for camel poisoning in the UAE.

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Area of Science:

  • Veterinary toxicology
  • Plant chemistry
  • Camelid health

Background:

  • Racing camels in the United Arab Emirates (UAE) are susceptible to poisoning.
  • Iphiona aucheri has been implicated in camel poisoning incidents.

Purpose of the Study:

  • To identify the toxic compounds in Iphiona aucheri responsible for poisoning racing camels.
  • To elucidate the chemical structures of these toxic principles.

Main Methods:

  • Isolation of chemical constituents from Iphiona aucheri.
  • Structure determination using spectroscopic methods.
  • Toxicological assessment of isolated compounds.

Main Results:

  • Terpenoids, a non-toxic pyrrolizidine alkaloid, atractyloside, and carboxyatractyloside were isolated.
  • The structures of atractyloside and carboxyatractyloside were confirmed.
  • Atractyloside and carboxyatractyloside were identified as the causative agents of Iphiona aucheri poisoning in camels.

Conclusions:

  • Atractyloside and carboxyatractyloside are the toxic principles of Iphiona aucheri.
  • These findings are crucial for managing and preventing camel poisoning in the UAE.

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