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Related Experiment Videos

Adrenocortical carcinoma: MR imaging appearance with current techniques

J F Schlund1, P J Kenney, E D Brown

  • 1Department of Radiology, University of North Carolina, Chapel Hill 17599-7510, USA.

Journal of Magnetic Resonance Imaging : JMRI
|March 1, 1995
PubMed
Summary

Magnetic resonance imaging (MRI) reveals key features of adrenocortical carcinoma (ACC). Common findings include hemorrhage, necrosis, and enhancing nodules, aiding in diagnosis.

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Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Adrenocortical carcinoma (ACC) is a rare but aggressive endocrine malignancy.
  • Accurate diagnosis and characterization of ACC are crucial for effective treatment planning.

Purpose of the Study:

  • To define the characteristic magnetic resonance (MR) imaging appearance of adrenocortical carcinoma (ACC) using contemporary MR techniques.
  • To identify consistent imaging features that aid in the diagnosis of ACC.

Main Methods:

  • Eight patients with confirmed ACC underwent high-field-strength MR imaging.
  • Utilized various sequences including T1-weighted, fat-suppressed T1 and T2-weighted, and gadolinium-enhanced sequences.
  • Acquired postcontrast images in sagittal and coronal planes, and out-of-phase images for specific evaluations.

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Main Results:

  • Consistent MR imaging features of ACC were identified in the study cohort.
  • Common findings included internal hemorrhage (7/8), central necrosis (7/8), and peripheral enhancing nodules (7/8).
  • Out-of-phase imaging demonstrated signal loss in two patients, suggesting a potential diagnostic clue.

Conclusions:

  • Current MR techniques can effectively depict characteristic features of adrenocortical carcinoma.
  • The identified MR imaging findings contribute to improved diagnostic accuracy for ACC.
  • MR imaging plays a vital role in the evaluation of suspected adrenocortical carcinoma, including assessment for metastatic disease.