Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fibrinogen and cardiovascular disorders

G Y Lip1

  • 1Department of Cardiology, Stobhill Hospital, Glasgow.

QJM : Monthly Journal of the Association of Physicians
|March 1, 1995
PubMed
Summary

High plasma fibrinogen levels increase cardiovascular disease risk by affecting blood viscosity and promoting clotting. This review explores the link between fibrinogen and conditions like stroke and heart disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

State of play and future direction with NOACs: An expert consensus.

Vascular pharmacology·2018
Same author

Glycative and oxidative stress are associated with altered thrombus composition in diabetic patients with ST-elevation myocardial infarction.

International journal of cardiology·2017
Same author

Reply to Jolobe

The journal of the Royal College of Physicians of Edinburgh·2017
Same author

Clinical Stroke prevention in atrial fibrillation.

The journal of the Royal College of Physicians of Edinburgh·2017
Same author

Short runs of atrial arrhythmia and stroke risk: a European-wide online survey among stroke physicians and cardiologists.

The journal of the Royal College of Physicians of Edinburgh·2016
Same author

'Patient choice' concept in AF ESC Guidelines: is the clinician giving up? Reply.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2013

Area of Science:

  • Biochemistry
  • Cardiovascular Medicine
  • Hematology

Background:

  • Plasma fibrinogen plays a key role in blood coagulation and viscosity.
  • Elevated plasma fibrinogen is linked to increased cardiovascular disease risk.
  • This protein may contribute to thromboembolic events and conditions like atrial fibrillation.

Purpose of the Study:

  • To review the association between plasma fibrinogen and cardiovascular disorders.
  • To examine the role of fibrinogen in blood viscosity and flow.
  • To understand fibrinogen's contribution to thromboembolic risk.

Main Methods:

  • Literature review of epidemiological and clinical studies.
  • Analysis of existing research on plasma fibrinogen and cardiovascular health.
  • Synthesis of evidence linking fibrinogen levels to disease risk.

Main Results:

  • Epidemiological data consistently show elevated plasma fibrinogen in cardiovascular disorders.
  • Increased fibrinogen levels correlate with higher risks of ischemic heart disease and stroke.
  • Fibrinogen contributes to a prothrombotic state, explaining risks in certain cardiac conditions.

Conclusions:

  • Plasma fibrinogen is a significant factor in cardiovascular health.
  • Elevated fibrinogen levels are a marker and potential contributor to cardiovascular events.
  • Understanding this association is crucial for managing cardiovascular and thromboembolic risks.

Related Experiment Videos