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[Systemic infection due to group A Streptococcus pyogenes]

T S Pohl1, P M Shah, A Hertel

  • 1Medizinische Klinik I, Universitätsklinikums Frankfurt.

Deutsche Medizinische Wochenschrift (1946)
|May 12, 1995
PubMed
Summary

Group A Streptococcus pyogenes caused severe necrotizing fasciitis in a woman, leading to abscesses and systemic complications. Prompt surgical intervention and antibiotics successfully treated the infection, resulting in full recovery.

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Area of Science:

  • Infectious Diseases
  • Dermatology
  • Rheumatology

Background:

  • Necrotizing fasciitis is a severe bacterial infection that can lead to rapid tissue destruction.
  • Group A Streptococcus pyogenes (GAS) is a common cause of various infections, including skin and soft tissue infections.

Observation:

  • A 47-year-old woman presented with oedematous swelling, joint pain, and fever, initially suspected as rheumatic disease.
  • Swollen areas progressed to abscesses requiring surgical incision and drainage.
  • Gallium scintigraphy identified a significant abscess over the left buttock.

Findings:

  • White blood cell count was elevated with a left shift, and blood sedimentation rate was high, indicating significant inflammation.
  • Histological examination of biopsies showed nonspecific inflammation.

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  • Blood cultures confirmed the presence of Group A Streptococcus pyogenes.

    • Implications:

    • This case highlights the increasing incidence of GAS-associated necrotizing fasciitis and its potential for severe systemic complications.
    • Early diagnosis, surgical debridement, and appropriate antibiotic therapy are crucial for successful management.
    • Increased awareness among clinicians is necessary for timely recognition and treatment of this aggressive infection.