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[A case report of intralobar sequestration associated with lung aspergillus]
M Tanaka1, H Miyamoto, Y Sakao
1Department of Respiratory Surgery, Mitsui Memorial Hospital, Tokyo, Japan.
Summary
This rare case report details a young woman with congenital lung disease, specifically intralobar sequestration, complicated by invasive pulmonary aspergillosis. Surgical resection successfully treated this unusual combination of conditions.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Infectious Diseases
Background:
- Congenital lung malformations like intralobar sequestration can predispose individuals to recurrent infections.
- Fungal infections, particularly invasive pulmonary aspergillosis, pose significant challenges in immunocompromised or structurally abnormal lungs.
Observation:
- A 21-year-old woman presented with fever and dyspnea, revealing a right lower lobe lung abscess on imaging.
- Percutaneous lung biopsy identified Aspergillus fumigatus, and aortic angiography revealed an aberrant artery supplying the affected lobe.
- A history of recurrent pneumonia suggested an underlying congenital lung abnormality.
Findings:
- The patient was diagnosed with intralobar sequestration (Pryce III type) associated with aspergillosis.
- Surgical intervention involved right lower lobectomy and ligation of the aberrant artery.
- Postoperative recovery was successful, with the condition attributed to a rare congenital anomaly and fungal infection.
Implications:
- This case highlights the rare but serious complication of invasive pulmonary aspergillosis in patients with intralobar pulmonary sequestration.
- Early diagnosis and surgical management are crucial for favorable outcomes in such complex cases.
- Further research into the pathogenesis and optimal treatment strategies for this rare association is warranted.