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Effects of lorazepam on human contrast sensitivity
1Department of Psychology, University of Reading, Earley Gate, Whiteknights, UK.
Psychopharmacology
|February 1, 1995
Abstract:
The anxiolytic lorazepam was studied for its effects on contrast sensitivity to gratings flickering in counterphase in normal volunteers. The drug significantly reduced contrast sensitivity at low spatial frequencies in a dose-related manner. The results are discussed with reference to possible GABA-mediated processes in the retina and lateral geniculate nucleus.