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Related Experiment Videos

Septic acute cholecystitis

C H Kuo1, C S Changchien, J J Chen

  • 1Division of Gastroenterology, Chang Gung Memorial Hospital, Kaohsiung Hsien, Taiwan.

Scandinavian Journal of Gastroenterology
|March 1, 1995
PubMed
Summary
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Bacteremia in acute cholecystitis (gallbladder inflammation) occurs in 7.65% of cases. When present, bacteremia significantly increases complications, mortality, and liver test abnormalities.

Area of Science:

  • Gastroenterology
  • Infectious Disease
  • Surgical Outcomes

Background:

  • Bacteremia is common in cholangitis but unexamined in acute cholecystitis.
  • Understanding bacteremia incidence is crucial for managing acute cholecystitis.

Purpose of the Study:

  • To determine the incidence of bacteremia in acute cholecystitis.
  • To analyze clinical manifestations, bacteriology, and outcomes associated with bacteremia in acute cholecystitis.

Main Methods:

  • Retrospective analysis of 78 patients with acute cholecystitis and positive blood cultures.
  • Matched comparison with 78 non-bacteremic acute cholecystitis patients.

Main Results:

  • Bacteremia prevalence was 7.65% (78/1020), with Escherichia coli and Klebsiella pneumoniae most common.

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  • Bacteremic patients showed elevated liver enzymes, increased complications (renal failure, septic shock), and 9.0% mortality.
  • Infected bile was the source in 80% of bacteremic cases.

    • Conclusions:

    • Bacteremia is infrequent but serious in acute cholecystitis.
    • Presence of bacteremia significantly elevates morbidity and mortality risks.