Eosinophil eicosanoid relations in allergic inflammation of the airways

Eosinophils are prominent features of allergic inflammation and can contribute to this process through release of inflammatory enzymes, granule-associated proteins, and leukotriene products. There is considerable interest in the fact that selected cytokines enhance eosinophil generation of leukotrienes. Therefore, future directions must include efforts to identify factors that regulate eosinophil synthesis of leukotrienes and therapeutic agents that might control these specific inflammatory responses.