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Acute interstitial nephritis associated with ticlopidine
H Rosen1, A S el-Hennawy, S Greenberg
1Department of Medicine, Coney Island Hospital, Brooklyn, NY 11235, USA.
Abstract:
Ticlopidine, a platelet aggregation inhibitor, has been approved to decrease the risk of thrombotic stroke. We describe a 75-year-old white woman who developed acute renal failure 10 days after initiating ticlopidine therapy. A renal biopsy revealed interstitial infiltrates containing lymphocytes and eosinophils. To our knowledge this is the first report of ticlopidine-induced acute interstitial nephritis.