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Updated: Aug 19, 2026
Measuring Bone Remodeling and Recreating the Tumor-Bone Microenvironment Using Calvaria Co-culture and Histomorphometry
Published on: March 14, 2020
The use of calvarial bone in nasal reconstruction
1Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, USA.
Objective:
To demonstrate the utility of calvarial bone as a primary graft choice in nasal reconstruction.
Design:
Case series.
Setting:
Academic tertiary care center. PATTERN: Thirty-five consecutive patients who underwent split calvarial bone grafting to the nasal dorsum between June 1988 and September 1993 and who had post-operative follow-up.
Outcome Measures:
Serial clinical examination to assess volume loss, movement of the graft, and complications. Standardized photographs to assess nasal contour.
Results:
Fixation of the graft was accomplished using a technique that promotes bone-to-bone healing without fixation screws or wires. The most common complication was seroma or hematoma of the scalp (8%). There were no dural tears or intracranial complications. Long-term donor site morbidity consisted of one case of local alopecia (2.8%). A good nasal contour was achieved in 97% of patients.
Conclusion:
Based on the experimental evidence reviewed and our clinical experience, split calvarial bone is recommended as a material of choice for nasal dorsal reconstruction.
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