Jove
Visualize
Contact Us

Related Experiment Videos

Bone marrow/allograft component therapy. A clinical trial

H D Skoff1

  • 1Harvard Medical School, Beth Israel Hospital, Boston, Massachusetts, USA.

American Journal of Orthopedics (Belle Mead, N.J.)
|January 1, 1995
PubMed
Summary

Autogenous bone marrow/cancellous allograft offers a viable alternative for bone grafting in skeletal defects. This study found 100% clinical healing and 95% radiographic union with no complications, supporting its use.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"Postpartum/newborn" de Quervain's tenosynovitis of the wrist.

American journal of orthopedics (Belle Mead, N.J.)·2001
Same author

Customizing bone anchors.

Plastic and reconstructive surgery·2000
Same author

The role of the abductor pollicis brevis in opposition.

American journal of orthopedics (Belle Mead, N.J.)·1998
Same author

A proximal interphalangeal joint fracture-dislocation treated by limited open (percutaneous) reduction and dynamic external fixation.

Plastic and reconstructive surgery·1997
Same author

Late infection of hand implant after a dental procedure: a case report.

American journal of orthopedics (Belle Mead, N.J.)·1997
Same author

Conservative open acromioplasty.

The Journal of bone and joint surgery. British volume·1995
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Orthopedics
  • Regenerative Medicine
  • Biomaterials

Background:

  • Skeletal defects necessitate bone grafting for healing, with autogenous iliac bone graft being the current standard.
  • The development of bone graft substitutes is crucial for addressing limitations of autogenous grafts.

Purpose of the Study:

  • To evaluate the efficacy of autogenous bone marrow/cancellous allograft as a substitute for iliac bone graft in patients with bony defects.
  • To assess both clinical and radiographic outcomes following the use of this bone graft substitute.

Main Methods:

  • A prospective study involving 19 consecutive patients with bony defects.
  • Autogenous bone marrow/cancellous allograft was used as the bone graft substitute.
  • Clinical and radiographic outcomes were monitored post-procedure.

Main Results:

  • 100% of patients achieved clinical healing at the grafting site.
  • 95% of patients demonstrated radiographic union.
  • No surgical or postoperative complications were reported in any patient.

Conclusions:

  • Autogenous bone marrow/cancellous allograft is a safe and effective alternative to autogenous iliac bone graft.
  • This allograft substitute demonstrates high rates of clinical and radiographic success in treating skeletal defects.
  • The findings support the use of bone marrow/allograft in orthopedic procedures requiring bone reconstruction.

Related Experiment Videos