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Translocation 11;14 in newly diagnosed chronic myelogenous leukemia
A Magdalinski1, H Drwinga, P Crilley
1Department of Neoplastic Diseases, Hahnemann University Hospital, Philadelphia, PA 19102, USA.
Cancer Genetics and Cytogenetics
|May 1, 1995
Abstract:
In patients with chronic myelogenous leukemia (CML), the Philadelphia chromosome may be associated with a number of other cytogenetic lesions. However, t(11;14)(q13;q32), found mainly in B-cell lymphoproliferative disorders, has not been previously reported in Ph-positive CML. We describe a patient with hematologically typical chronic phase CML in whom both cytogenetic lesions were found at diagnosis.