Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Evoked potentials]

R Kakigi1

  • 1Department of Integrative Physiology, National Institute for Physiological Sciences.

Rinsho Shinkeigaku = Clinical Neurology
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Pain-related somatosensory evoked potentials (pain SEPs) show distinct patterns in healthy individuals. These pain SEPs are valuable for detecting sensory impairments and understanding pain modulation mechanisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Warm-, hot- and pain-related neural activities depending on baseline skin temperatures.

European journal of pain (London, England)·2018
Same author

Heat stress-induced phosphorylation of FoxO3a signalling in rat skeletal muscle.

Acta physiologica (Oxford, England)·2016
Same author

Effects of walking combined with restricted leg blood flow on mTOR and MAPK signalling in young men.

Acta physiologica (Oxford, England)·2014
Same author

Heat stress activates the Akt/mTOR signalling pathway in rat skeletal muscle.

Acta physiologica (Oxford, England)·2012
Same author

Effects of acute nicotine on somatosensory change-related cortical responses.

Neuroscience·2012
Same author

Effects of ageing and endurance exercise training on alpha-actinin isoforms in rat plantaris muscle.

Acta physiologica (Oxford, England)·2011
Same journal

[Let's present at a regional meeting].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Editor's Note].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Notice for Members].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[The Proceedings of the 250th Kyushu Regional Meeting of the Japanese Society of Neurology].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[The Proceedings of the 116th Tohoku Regional Meeting of the Japanese Society of Neurology].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Metagenomic analysis for central nervous system infections: clinical utility and future directions].

Rinsho shinkeigaku = Clinical neurology·2026
See all related articles

Area of Science:

  • Neuroscience
  • Pain research
  • Somatosensory system

Context:

  • Evoked potentials, particularly pain-related somatosensory evoked potentials (pain SEPs) using CO2 laser stimulation, represent a significant advancement in pain research.
  • Specific potentials, N240-P340 and N300-P400, are identified following hand and foot stimulation in normal subjects, respectively.
  • Conduction velocity in A delta fibers and the spinothalamic tract is approximately 10 m/sec.

Purpose:

  • To summarize recent advances in pain-related somatosensory evoked potentials (pain SEPs).
  • To explore the relationship between pain perception, movement, and inhibitory controls.
  • To evaluate the clinical utility of pain SEPs in assessing pain sensation and detecting subclinical lesions.

Summary:

  • Pain SEPs demonstrated decreased amplitude with vibration-induced pain relief, supporting the gate control theory.

Related Experiment Videos

  • Limb movements adjacent to or remote from the stimulation site significantly reduced pain SEP amplitude, indicating interactions between pain perception and motor activity.
  • Diffuse noxious inhibitory controls (DNIC) were confirmed by pain SEPs, highlighting their role in pain modulation.

    • Impact:

    • Pain SEPs correlate significantly with clinical pain sensation impairments.
    • Subclinical lesions in ascending pain pathways can be detected using pain SEPs.
    • Pain SEPs offer a valuable tool for clinical assessment of pain pathways and sensory function.