[Study on the collagen of the different region of disc and different sigmental disc]

With the method of the collagen decomposition producting special hyoroxyprolines (HYP), the collagens of the different region of discs and different segmental discs were studied. The results were as follow: The fibrous annulus had a higher collagen content than did the nucleus pulposus (P < 0.001). In fibrous annulus, the inner region had a lower collagen content was found at the postolateral part of the fibrous annulus (P < 0.05), especially at the poster-lateral inner zone (P < 0.001). The local low-collagen content at the particular location may be one of the factors, which was clinically susceptible to a disc herniation at the part. An increasing graduation of collagen content was found from thoracic disc12 to lumbar disc 5. But, there was no statistically significant difference (P > 0.05).