Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transtracheal needle aspiration

D H Roche1, M L Wilsher, A M Gurley

  • 1Department of Cytology, Green Lane Hospital, Auckland, New Zealand.

Diagnostic Cytopathology
|March 1, 1995
PubMed
Summary

Adding a cytopathologist during transtracheal needle aspiration biopsies significantly improves diagnostic accuracy for lung cancer staging and mediastinal adenopathy. This technique enhances diagnostic yield compared to procedures without pathology consultation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bone density is normal and does not change over 2 years in sarcoidosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2014
Same author

Hypoxic pulmonary vasoconstriction as a contributor to response in acute pulmonary embolism.

Annals of biomedical engineering·2014
Same author

Pulmonary embolism: predicting disease severity.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2011
Same author

Does CT scanning predict the likelihood of a positive transbronchial biopsy in sarcoidosis?

Thorax·2009
Same author

Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society.

Thorax·2008
Same author

Exhaled nitric oxide in sarcoidosis.

Thorax·2005

Area of Science:

  • Pulmonology
  • Oncology
  • Cytopathology

Background:

  • Transtracheal needle aspiration biopsy is a procedure used for diagnosing lung cancer and mediastinal adenopathy.
  • Optimizing diagnostic yield in these biopsies is crucial for patient management and treatment planning.

Observation:

  • A review of 27 transtracheal needle aspiration biopsies was conducted.
  • Procedures were performed using a rigid bronchoscope and needle, with a cytopathologist present for 11 biopsies.
  • The presence of a cytopathologist allowed for immediate assessment of specimen adequacy and on-site repeat biopsies if necessary.

Findings:

  • Biopsies performed with a cytopathologist in attendance yielded a diagnosis in 81% of cases (9/11).
  • In contrast, only 18.8% of biopsies (3/16) were diagnostic when performed without pathologist consultation.
  • All initially negative biopsies were confirmed to have disease (sarcoidosis or cancer) by subsequent investigations.

Implications:

  • The integration of cytopathology services during rigid bronchoscopy with needle aspiration substantially increases diagnostic sensitivity.
  • This approach is highly effective for staging bronchogenic carcinoma and diagnosing mediastinal adenopathy.
  • On-site pathology review is recommended to improve the diagnostic accuracy of transtracheal needle aspiration biopsies.

Related Experiment Videos