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Related Experiment Videos

Stress protection due to external fixation

D M O'Doherty1, S P Butler, A E Goodship

  • 1School of Engineering, University of Wales College of Cardiff, U.K.

Journal of Biomechanics
|May 1, 1995
PubMed
Summary

External fixators with intact bars significantly reduce bone strain, leading to bone loss through resorption. This stress protection effect persists over time, impacting bone remodelling.

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Area of Science:

  • Orthopaedic biomechanics
  • Bone biology
  • Skeletal remodelling

Background:

  • Bone is sensitive to mechanical stimuli.
  • Orthopaedic devices can alter the mechanical environment of bone.
  • Understanding these alterations is crucial for bone repair and remodelling.

Purpose of the Study:

  • To investigate the mechanical effects of an Oxford External Fixator on ovine tibiae.
  • To quantify the impact of fixator configuration on bone strain and mineral content.
  • To assess the long-term bone remodelling response to stress protection.

Main Methods:

  • Application of Oxford External Fixator to ovine tibiae.
  • Strain gauge measurements during normal walking with intact and sectioned fixator bars.
  • Longitudinal assessment of bone mineral content and remodelling over 16 weeks.

Main Results:

  • An intact fixator bar significantly reduced peak bone strains compared to a sectioned bar, indicating stress protection.
  • Stress-protected bone (intact bar) showed a 9% decrease in bone mineral content over 16 weeks compared to unprotected bone (sectioned bar).
  • Bone loss occurred due to periosteal and endosteal resorption in the stress-protected limb.

Conclusions:

  • External fixators with intact bars induce significant stress protection in bone.
  • This stress protection leads to decreased bone mineral content and increased resorption.
  • Fixator design critically influences the mechanical environment and subsequent bone remodelling.

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