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Endophthalmitis after pars plana vitrectomy. The Postvitrectomy Endophthalmitis Study Group
S M Cohen1, H W Flynn, T G Murray
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, FL, USA.
Ophthalmology
|May 1, 1995
Summary
Postvitrectomy endophthalmitis is a rare complication following vitrectomy surgery. Infections caused by bacteria other than coagulase-negative staphylococci are associated with poor visual outcomes.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Surgical Outcomes
Background:
- Postvitrectomy endophthalmitis is a serious complication following intraocular surgery.
- Understanding its incidence and clinical course is crucial for patient management.
Purpose of the Study:
- To determine the incidence and clinical characteristics of culture-proven postvitrectomy endophthalmitis.
- To analyze visual acuity outcomes based on causative organisms.
Main Methods:
- Retrospective review of 18 patients diagnosed with postvitrectomy endophthalmitis across multiple centers.
- Exclusion of patients with recent trauma or pre-existing endophthalmitis.
- Analysis of causative organisms, treatment, and final visual acuity.
Main Results:
- The incidence of endophthalmitis after pars plana vitrectomy was 0.07% (9/12,216 eyes).
- Coagulase-negative staphylococci (CoNS) were identified as a common cause.
- Eyes infected with CoNS had significantly better visual outcomes (71% with ≥20/50 acuity) compared to other organisms (P=0.005).
- Poor visual acuity (<5/200) was observed in 11 eyes, with 9 eyes having no light perception.
Conclusions:
- Postvitrectomy endophthalmitis is a rare but sight-threatening complication.
- Bacterial endophthalmitis caused by organisms other than CoNS portends a poor visual prognosis.
- Prompt treatment with intraocular antibiotics is essential for managing this condition.