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[Comparative study of the extension of coronary arteriosclerosis with risk factors and changes in the retinal artery]
W C Manfroi1, J Lavinski, R da C Ferreira
1Hospital de Clínicas da Faculdade de Medicina da UFRS, Porto Alegre.
Insights
Male sex and cigarette smoking are linked to more severe coronary artery disease. Other common risk factors and retinal changes showed no significant association with coronary artery disease extent.
Area of Science:
- Cardiology
- Ophthalmology
- Public Health
Background:
- Coronary artery disease (CAD) is a leading cause of mortality worldwide.
- Identifying CAD risk factors is crucial for prevention and management.
- Retinal arteriolar changes are sometimes used as indicators of systemic vascular health.
Purpose of the Study:
- To investigate the association between the extent of coronary artery disease (CAD).
- To examine the relationship between CAD and traditional cardiovascular risk factors.
- To explore the correlation between CAD and retinal arteriolar changes observed during fundoscopic examination.
Main Methods:
- A cohort of 96 patients (66 males, aged 36-72) underwent selective cinecoronaryarteriography.
- Patients were assessed for risk factors including smoking, diabetes, dyslipidemia, hypertension, age, alcoholism, sex, family history, and obesity.
- Fundoscopic examinations were performed to evaluate retinal arteriolar changes.
Main Results:
- Male sex (p < 0.001) and current cigarette smoking (p < 0.01) were significantly associated with a greater extent of coronary artery disease.
- No statistically significant relationships were found between the extent of CAD and other evaluated risk factors.
- No significant association was observed between the extent of CAD and observed retinal arteriolar changes.
Conclusions:
- Male sex and cigarette smoking are significant predictors of the extent of coronary artery disease.
- Traditional risk factors such as diabetes, hypertension, and dyslipidemia were not significantly related to CAD extent in this cohort.
- Retinal arteriolar changes did not correlate with the extent of coronary artery disease in this study population.
Purpose:
To identify a possible relationship of the extent of coronary artery disease, with risk factors for coronary artery disease and the retinal arteriolar changes (evaluated by fundoscopic examination).
Methods:
We studied 96 patients (66 males), 36 to 72 years of age. All patients were studied by selective cinecoronaryarteriography, fundoscopic examination, as well as evaluated for the common risk factors, cigarette smoking diabetes, dislipidemia, systemic hypertension, age, alcoholism, male sex, family history and obesity.
Results:
Male (p < 0.001) and smoking (p < 0.01) were the statistically significant associations with the extent of coronary artery disease. No significant relationship with the extent of coronary artery disease was present for the other risk factor nor for changes in retinal arteriolar branches.
Conclusion:
A relationship between extent of coronary artery disease with male sex and a cigarette smoker is occurred. No relationship with other risk factors, nor with retinal arteriolar changes were present.